Articles

Azilsartan for BP reduction: Meta-analysis of RCTs

A meta analysis of randomized controlled trials of azilsartan for the reduction of blood pressure BP in patients with hypertension was published in the journal Hypertension Research. Researchers searched MEDLINE EMBASE and the Cochrane Central Register of Controlled Trials right from the outset of the records up to March 2013 using web based search engines PubMed and OVID . Prospective randomized controlled trials of azilsartan including azilsartan

Read more
Effects of cilnidipine on fibrinolysis in hypertensive patients

Fibrinolysis has an important role to play in atherogenesis. A study published in Clinical Drug Investigation explored the effects of cilnidipine on fibrinolysis in hypertensive patients. This was an open label paired trial including 43 patients with mild to moderate hypertension. Following a 2 week placebo washout period patients were given cilnidipine 5mg daily for 8 weeks. After treatment with cilnidipine plasma tissue plasminogen activator tPA

Read more
Vildagliptin enhances restoration of salivary glands impaired by obese-insulin resistance.

A new study published in the Archives of Oral Biology hypothesized that that vildagliptin confers beneficial effects on the salivary gland impaired by obese insulin resistance via decreasing mitochondrial dysfunction apoptosis oxidative stress and inflammation. In this experiment 24 male Wistar rats were divided into two groups. Each group was fed with either a normal diet ND or a high fat diet HFD for 16 weeks. At week 13 the HFD fed rats were subdivided

Read more
NIH launches PregSource, a crowdsourcing project to better understand pregnancy

The National Institutes of Health has launched PregSource a research project that aims to improve knowledge of pregnancy by collecting information directly from pregnant women on November 1 2017. Pregnant women can track their experiences through a secure and confidential website. By offering a more comprehensive picture of the pregnancy experience from normal pregnancies to those complicated by disease or other factors PregSource promises to inform

Read more
A history of kidney stones is associated with metabolic and hypertensive complications during pregnancy

Results from a new study presented at ASN Kidney Week 2017 in New Orleans Louisiana suggest that a history of kidney stones may indicate an increased risk for metabolic and hypertensive complications during pregnancy and add support to a growing body of research linking kidney stones with systemic diseases such as diabetes and cardiovascular disease.

Read more
New clinical practice guidelines for seasonal allergic rhinitis

New clinical practice guideline for treatment of seasonal allergic rhinitis SAR has been published November 7 2017 in Annals of Allergy Asthma and Immunology. The guidelines recommend that For initial treatment of SAR in adults clinicians should routinely prescribe monotherapy with an intranasal corticosteroid ICS rather than ICS in combination with an oral antihistamine. For initial treatment of SAR in adults clinicians should recommend an ICS over

Read more
Kala Azar linked with a new virus

Researchers have found evidence of an unknown virus that may be responsible for the persistence of Kala-azar or Visceral leishmaniasis. Though it is early to link the virus with this parasitic infection but its discovery would give way for a new kind of treatment regime and may help in eradication of the disease. Also a group of scientists from West Bengal and Uttar Pradesh in India, said that another parasite may be involved. Another parasite called

Read more
Pterygium

A Pterygium is a triangular sheet of fibrovascular tissue over the conjunctiva, which invades the cornea. It has three parts - head or apex, neck and the body.  It frequently follows a Pinguecula. The nasal side is affected first but it may be bilateral. Numerous small opacities i.e. deposits of iron (Stockers Line) may lie in front of blunt apex of Pterygium.  It is a degenerative condition of the subconjunctival tissue which proliferates as vascularised

Read more
Zinc supplements can significantly inhibit the proliferation of esophageal cancer cells

Zinc supplements can significantly inhibit the proliferation of esophageal cancer cells, according to a new study co-authored by a Arlington researcher at University of Texas.  In this study, a team led by Zui Pan, an associate professor of nursing at UTA's College of Nursing and Health Innovation and a noted esophageal cancer researcher, discovered that zinc selectively halts the growth of cancer cells but not normal esophageal epithelial cells.

Read more
Lyres Sign – in Carotid Body Tumor.

LYRE SIGN - Splaying of the Internal and External Carotid arteries by a carotid body tumour, at carotid bifurcation.

Read more